Manufacturer of Preclinical Imaging Instruments
Specialising in Advanced Benchtop Instruments
for in vivo Molecular Imaging
Drug Studies • Neuroscience • Cardiology • Cancer Research • Theranostics • Biodistribution
TriFoil’s InSyTeTM Series provides
Radioisotope-free, 3D molecular imaging
Benchtop imaging series which offers 3D complete angle fluorescence tomography (FLECT™) together with CT in an easy to use package.
The systems can be configured with FLECT™ and CT or CT alone.
Each has a simple, consistent user-friendly interface for image reconstruction and co-registration.
What is Fluorescence Emission Computed Tomography (FLECT™)?
FLECT™ technology utilizes complete angle tomography in a preclinical optical imaging system. The system acquires fluorescence data from specific molecular markers in 360° utilising a ring of detectors around the mouse. The fluorescence is then reconstructed in 3D using a computational reconstruction algorithm that models light propagation in tissue such that the molecular markers can be correctly visualized within the target tissue. The data is analogous to that generated by PET or SPECT systems, without the use of radioisotopes.
- Gives 360° Tomographic Capability
- With High Sensitivity and Resolution
- In Easy-to-use, Compact System
FLECT is a convenient and affordable alternative to ionizing radiation based molecular imaging methods to give researchers
- In vivo assessment (non-invasive)
- Specific visualization (molecular)
- Specific localization (depth)
Optical Imaging in 2D, 3D
2D planar optical imaging > 2D image > 2D localization > Fast Screening
3D optical tomography ➤ Visualization in 3D ➤ Localization in 3D ➤ Depth information
Combined with X-ray CT
InSyTe CT is perfectly equipped to allow for high soft tissue contrast CT imaging, providing necessary anatomical information for physiological studies as well as high bone contrast imaging for various anatomical investigations.
Features
- Complete angle 3D fluorescence tomography
- State-of-the-art 3D image reconstruction engine
- Quantitative molecular optical imaging
- In line X-ray CT
- Possible co-registration with other tomographic imaging modalities
- Gas anaesthesia inlet/outlet ports
Applications
- Oncology
- Cardiology
- Gene expression
- Therapeutic Response
- Bio-distribution
- Neuroscience